Follow the links below:



Thiery, T., Lajnef, T, Combrisson, E., Dehgan, A., Rainville, P., Mashour, G., Blain-Moraes, S., and Jerbi, K.  (2018). Long-range temporal correlations in the brain distinguish conscious wakefulness from induced unconsciousness. NeuroImage, 179, 30-39.; doi: 10.1016/j.neuroimage.2018.05.069.

Wan, A.K., Rainville, P., O’Leary, S., Elphinston, R.A., Larivière, C., and Sullivan, M.J.L. (accepted). Validation of an index of sensitivity to movement evoked pain in patients with whiplash injuries. Pain Reports.

Laverdure-Dupont, D., Rainville, P., Renancio, C., Montplaisir, J., et Lavigne, G. (accepted). Placebo analgesia persists during sleep: an experimental study. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 85, 33-38. , doi: 10.1016/j.pnpbp.2018.03.027.

Lévy, S., Guertin, M.-C., Khatibi, A., Mezer, A., Martinu, K., Chen, J.-I, Stikov, N., Rainville, P., and Cohen-Adad, J. (2018). Test-retest reliability of myelin imaging in the human spinal cord: Measurement errors versus region- and aging-induced variations. PLoS-One; : e0189944;;  doi: 10.1371/journal.pone.0189944


Emami, E., Gosselin, N. and Rainville, P. (2017). Culturally-adapted musical intervention for patient-centered health care. Journal of the Canadian Dental Association (JCDA), 83, h13.

Ladouceur, A., Rustamov, N., Dubois, J.-D., Tessier, J., Lehmann, A., Descarreaux, M., Rainville, P., and Piché, M. (in press). Inhibition of pain and pain-related brain activity by heterotopic noxious counter-stimulation and selective attention in chronic non-specific low back pain. Neuroscience, pii: S0306-4522(17)30716-9;; doi: 10.1016/j.neuroscience.2017.09.054.

Elphinston, R., Thibault, P., Carriere, J.S., Rainville, P., Sullivan, M.J.L. (2017). Cross-sectional and prospective correlates of recovery expectancies in the rehabilitation of whiplash injury. Clin. J. Pain, 34, 306-312; , doi: 10.1097/AJP.0000000000000542

Khoshnejad, M., Roy, R., Martinu, K., Chen, J.-I, Cohen-Adad, J., Grondin, S., and Rainville, P. (2017). Brain processing of the temporal dimension of acute pain in short-term memory. Pain, 158, 2001-11. doi: 10.1097/j.pain.0000000000001003.

Taylor, V.A., Chang, L., Rainville, P., Roy, M. (2017). Learned expectations and uncertainty facilitate pain during classical conditioning. Pain, 158, 1528-1537. , doi: 10.1097/j.pain.0000000000000948.

Mankovsky-Arnold, T., Wideman, T.H., Thibault, P., Larivière, C., Rainville, P., and Sullivan, M.J.L. (in press). Sensitivity to Movement-Evoked Pain and Multi-Site Pain are Associated with Work-Disability Following Whiplash Injury: A Cross-Sectional Study. Journal of Occupational Rehabilitation, 27, 413-421 DOI:10.1007/s10926-016-9672-z

Ghaziri, J., Tucholka, A. Girard, G., Houde, J-C., Gilbert, G., Descoteaux, M., Rainville, P., Nguyen, D. K. (2017). The cortico-cortical structure of the human insula, Cerebral Cortex, 27, 1216-1228.


Vachon-Presseau, E., Roy, M., Woo, C.W., Kunz, M., Martel, M.-O., Sullivan, M.J.L., Jackson, P.L., Wager, T.D., and Rainville, P. (2016). Multiple faces of pain: Effects of chronic pain on the brain regulation of facial expression. Pain, 157:1819-30. doi: 10.1097/j.pain.0000000000000587 ; .

Khoshnejad, M., Martinu-Aurousseau, K., Grondin, S., and Rainville, P. (2016). The delayed reproduction of long time intervals defined by innocuous thermal sensation. Experimental Brain Research,  Doi: 10.1007/s00221-015-4537-9;

Cormier, S., Lavigne, G.L., Choinière, M., and Rainville, P. (2016). Expectations and outcomes of chronic pain treatment: the mediating effect of patients’ global impression of change. Pain, 157, 329-338. doi: 10.1097/j.pain.0000000000000379.

Denis, D.J., Marouf, R., Rainville, P., Bouthillier, A. et Nguyen, D.K. (2016). Effects of insular stimulation on thermal nociception. Eur. J. Pain, 20, 800-810.


Duncan, NW, Hayes, DJ, Wiebking, C, Tiret, B, Pietruska, K, Rainville, P, Marjanska, M., Mohammid, O, Doyon, J, Northoff, G (2015). Negative childhood experiences alter a prefrontal-insular-motor cortical network in healthy adults: A preliminary multimodal rsfMRI-fMRI-MRS-dMRI study. Human Brain Mapping.

Mancini-Marïe, A. Yoon, U., Jiminez, J., Fahim, C, Potvin, S., Grant, J.A., Laverdure-Dupont, D., Dubé, A-A, Betrisey, C., Rainville, P., Evans, A.C., Stip, E. and Mendrek, A. (2015). Sex, age, symptoms and illness duration and their relation with gyrification index in schizophrenia. Clin Schizophr Relat Psychoses. 2015 Jul 28. [Epub ahead of print].

Marouf, R., Piché, M., Rainville, P. (in press). Is temporal summation of pain and spinal nociception altered during normal aging? Pain. 

Lévy, S., Benhamou, M., Naaman Rainville, P., Callot, V. et Cohen-Adad, J. (2015). White matter atlas of the human spinal cord with estimation of partial volume effect. Neuroimage, 119, 262-271. doi: 10.1016/j.neuroimage.2015.06.040,

Roy, C., Blais, C., Fiset, D., Rainville, P., and Gosselin, F. (2015). Efficient information for recognizing pain in facial expressions. Eur J of Pain, 19, 852-860. doi: 10.1002/ejp.676;

Budell, L., Kunz, M., Jackson, P. and Rainville. P. (2015). Mirroring pain in the brain: emotional expression versus motor imitation. PLoS On 10(2):e0107526. doi: 10.1371/journal.pone.0107526


Khatibi, A., Vachon-Presseau, E., Schrooten, M., Vlaeyen, JWS, and Rainville, P. (2014). Attention effect on vicarious modulation of spinal nociception and pain. Pain, 155, 2033-2039.

Khoshnejad, M., Piché, M., Saleh, S, Duncan, G. and Rainville, P. (2014). Serial processing of noxious and innocuous information in primary and secondary somatosensory cortex. Neuroscience letters.577, 83-99.

Khoshnejad, M., Fortin, M.-C., Rohani, F., Duncan, G. and Rainville, P. (2014). Remembering the dynamic changes in pain intensity and unpleasantness: a psychophysical study. Pain, 155, 581-590.

Marouf, R., Caron, S., Lussier, M., Bherer, L., Piché, M., Rainville, P. (2014). Reduced pain inhibition is associated with reduced cognitive inhibition in healthy aging. Pain, 155, 494-502.


Arsenault, M., Ladouceur, A., Lehmann, A., Rainville, P., Piché, M. (2013). Pain modulation induced by respiration: phase and frequency effects. Neuroscience, 252, 501-11. (doi: 10.1016/j.neuroscience.2013.07.048.

Roy, C., Fiset, D., Taschereau-Dumouchel, V., Gosselin, F., and Rainville, P. (2013). A refined examination of the facial cues contributing to vicarious effects on self-pain and spinal responses. J of Pain, 14, 1475-84(doi: 10.1016/j.jpain.2013.07.011)

Vachon-Presseau, E., Martel, M.-O., Roy, M., Albouy, G., Sullivan, M.J.L., Jackson, P.L., and Rainville, P. (2013). The two sides of pain communication: effects of pain expressiveness on vicarious brain responses revealed in chronic back pain patients. J of Pain, 14, 1407-15.

Piché, M., Chen, J.-I., Roy, M., Poitras, P., Bouin, M., Rainville, P.(2013). Thicker posterior insula is associated with disease duration in women with irritable bowel syndrome (IBS) while thicker orbitofrontal cortex predicts reduced pain inhibition in both IBS and controls. J of Pain, 14, 1217-26 (

Silvestrini, N. and Rainville, P. (2013). After-effects of cognitive control on pain.  Eur J Pain, 17, 1225-33 (doi: 10.1002/j.1532-2149.2013.00299.x.).

Vachon-Presseau, E., Martel, M.-O., Roy, M., Caron, E., Albouy, G., Marin, M.-F., Plante, I., Sullivan, M.J.L., Lupien, S.J., and Rainville, P. (2013). Acute stress contributes to individual differences in pain and pain-related brain activity in healthy and chronic pain patients. Journal of Neuroscience, 33(16), 6826-33.

HayesD.J., Duncan,N.W., Wiebking, C., Pietruska, K., Qin, P., Lang, S., Gagnon,J., Gravel, P., Verhaeghe, J., Kostikov, A.P., Schirrmacher, R., Reader, A.J., Doyon, J., Rainville, P., Northoff, G. (2013). GABAA receptors predict aversion-related brain responses: An fMRI-PET investigation in healthy humans. Neuropsychopharmacology, 38, 1438-50.

Vachon-Presseau, E., Roy, M., Martel, M.-O., Caron, E., Marin, M.-F., Chen, J.-I.; Albouy, G., Plante, I., Sullivan, M.J.L., Lupien, S.J., and Rainville, P. (2013). The stress model of chronic pain: evidence from basal cortisol and hippocampal structure and function in human.  Brain. 136, 815-27.

Cormier, S., Piché, M., and Rainville, P. (2013). Expectations modulate heterotopic noxious counter-stimulation analgesia. Journal of Pain, 14, 114-25. (doi: 10.1016/j.jpain.2012.10.006)

Grant, J.A., Duerden, E.G., Courtemanche, J., Cherkasova, M., Duncan, G.H. and Rainville, P. (2013). Cortical thickness, mental absorption and meditative practice: possible implications for disorders of attention. Biological Psychology, 92, 275-281. (doi: 10.4155/bio.12.258)

Arsenault, M., Piché, M., Duncan, G.H., and Rainville, P. (2013). Self-regulation of acute experimental pain with and without biofeedback using spinal nociceptive responses. Neuroscience, 231, 102-10 (


Xie, G., Piché, M., Khoshnejad, M., Perlbarg, V., Chen, J.-I., Hoge, R., Benali, H., Rossignol, S., Rainville, P., and Cohen-Adad, J.  (2012). Reduction of physiological noise with independent component analysis improves the detection of nociceptive responses with fMRI of the human spinal cord. Neuroimage, 63, 245-52.

Vachon-Presseau, E., Roy, M., Martel, M.O., Albouy, G., Chen, J.-I., Budell, L., Sullivan, M.J., Jackson, P.L., and Rainville, P. (2012). Brain processing of sensory and emotional-communicative information from which vicarious pain is perceived. Neuroimage, 63, 54-62.

Ladouceur, A., Tessier, J., Provencher, B., Rainville, P., and Piché, M. (2012). Top-down attentional modulation of analgesia induced by heterotopic noxious counter-stimulation. Pain, 153, 1755-1762.

Coll, M.-P., Budell, L., Rainville, P., Decety, J., and Jackson, P.L. (2012) The role of gender in the interaction between self-pain and the perception of pain in others. Journal of Pain, 13, 695-703.

Mailhot, J.-P., Vachon-Presseau, E., Jackson, P.L., and Rainville, P. (2012). Dispositional empathy modulates vicarious effects of dynamic pain expressions on spinal nociception, facial responses and acute pain. Eur J Neurosci. 35, 271-8.

Kunz, M., Lautenbacher, S., LeBlanc, N., and Rainville, P. (2012). Are both the sensory and the affective dimensions of pain encoded in the face? Pain, 153, 350-8.

Roy, M., Lebuis, A., Hugueville, L., Peretz, I., and Rainville, P. (2012). Spinal modulation of nociception by music. Eur J of Pain, 16, 870-7.


Piché, M., Bouin, M., Arsenault, M., Poitras, P., Rainville, P. (2011). Decreased pain inhibition in irritable bowel syndrome depends on altered descending modulation and higher-order brain processes. Neuroscience, 195, 166-75.

Hadjistavropoulos, T. Craig, K.D., Duck, S., Cano, A.M., Goubert, L., Jackson, P.L., Mogil, J.S., Rainville, P., Sullivan, M.J.L., de C Williams, A., Vervoort, T, Dever Fitzgerald, T. (2011). A biopsychosocial formulation of pain communication. Psychological Bulletin, 137, 910-39; Epub 2011 May 30,

Goffaux, P., Michaud, K., Gaudreau, J., Chalaye, P., Rainville, P., and Marchand, S. (2011). Sex differences in perceived pain are affected by an anxious brain. Pain, 152, 2065-73.

Vachon-Presseau, E., Martel, M.-O., Roy, M., Caron, E. Jackson, P.L., and Rainville, P. (2011) The multilevel organization of vicarious pain responses: effects of pain cues and empathy trait on spinal nociception, autonomic response and acute pain. Pain, 152(7), 1525-31.

Kunz, M., Chen, J.I., Lautenbacher, S., Vachon-Presseau, E., and Rainville, P. (2011). Cerebral regulation of facial expressions of pain. J. Neurosci.31, 8730-38.

Kunz, M., Rainville, P., and Lautenbacher, S. (2011). Operant conditioning of facial pain displays. Psychosomatic Medicine, 73, 422-31.

Roy, M., Lebuis, A., Peretz, I., and Rainville, P. (2011). The modulation of pain by attention and emotion: A dissociation of perceptual and spinal nociceptive processes. European J of Pain, 15, 641.e1-641.e10 (

Grant, J.A., Courtemanche, J., and Rainville, P. (2011). A non-elaborative mental stance and decoupling of executive and pain-related cortices predicts low pain sensitivity in Zen meditators. Pain,152, 150-6; e-pub 4 nov. 2010;doi:10.1016/j.pain.2010.10.006.


Budell, L.C., Jackson, P.L., and Rainville, P. (2010). Brain responses to facial expressions of pain: emotional or motor mirroring? NeuroImage, 53, 355-365 (

Lungu, O., Piché, M., Frigon, A., Rainville, P., Rossignol, S. and Doyon, J. (2010). Changes in spinal cord excitability associated with motor sequence learning. J Neurophysiol 103, 2675-2683. (

Piché, M., Arsenault, M., and Rainville, P. (2010). Dissection of perceptual, motor and autonomic components of brain activity evoked by noxious stimulation. Pain, 149, 453-462 (

Grant, J.A., Courtemanche, J.,  Duerden, E.G., Duncan, G.H. and Rainville, P. (2010). Cortical thickness and pain sensitivity in Zen meditators. Emotion, 10, 43-53. Summary of this report by Constance Holden published in Science, March 2010.

Piché, M., Arsenault, M., Poitras, P., Rainville, P., Bouin, M. (2010). Widespread hypersensitivity is related to altered pain inhibition processes in irritable bowel syndrome. Pain, 148, 49-58 (doi:10.1016/j.pain.2009.10.005); featured in a review by Cathy Price: Faculty of 1000 Medicine, 23 Nov 2009;

Dufresne, A., Rainville, P., Dodin, S., Barré, P., Masse, B., Verreault, R., et Marc, I. (2010). Hypnotizability and opinions about hypnosis in a clinical trial for the hypnotic control of pain and anxiety during pregnancy termination. International Journal of Clinical and Experimental Hypnosis, 58: 82-101.


Roy, M., Piché, M., Chen, J.I., Peretz, I., and Rainville, P. (2009). Cerebral and spinal modulation of pain by emotion. PNAS, 106, 20900-05 (doi:10.1073/pnas.0904706106).

Piché, M., Arsenault, M., and Rainville, P. (2009). Cerebral and cerebrospinal processes underlying counterirritation analgesia. Journal of Neuroscience  29, 14236-46. (doi:10.1523/JNEUROSCI.2341-09.2009).

Laverdure-Dupont, D., Rainville, P.,  Montplaisir, J., et Lavigne, G. (2009). Changes in REM sleep associated with placebo-induced expectations and analgesia. Journal of Neuroscience, 29, 11745-52;

Albanese, M-.C., Duerden, E.G., Bohotin, V., Rainville, P., Duncan, G.H. (2009). Differential effects of cognitive demand on human cortical activation associated with vibrotactile stimulation. J Neurophysiology, 102, 1623-1631; doi:10.1152/jn.91295.2008 0022-3077/09.

Marc, I., Rainville, P., Masse, B., Dufresne, A., Verreault, R., Vaillancourt, L., et Dodin, S. (2009). Women’s views in a trial to evaluate hypno-analgesia for pain and anxiety relief during first-trimester pregnancy termination. Journal of Women’s health, 18, 1441-1447; doi:10.1089/jwh.2008.1015.

Ditto, B., Lewkowski, M.D., Rainville, P., et Duncan, G.H. (2009). Effects of Cardiopulmonary Baroreceptor Activation on Pain May Be Moderated by Risk for Hypertension. Biological Psychology, 82, 211-213; doi:10.1016/j.biopsycho.2009.07.009.

Dubé, A.-A., Duquette, M., Roy, M., Lepore, F., Duncan, G.H., and Rainville, P. (2009). Brain activity associated with the electrodermal reactivity to acute heat pain. NeuroImage, 45, 169-180.

Grant, J.A., and Rainville, P. (2009). Pain sensitivity and analgesic effects of mindful states in Zen meditators: a cross-sectional study. Psychosomatic Medicine, 71, 106-114; DOI: 10.1097/PSY.0b013e31818f52ee.

Piché, M., Cohen-Adad, J., Khoshnejad, M., Perlbarg, V., Xie, G., Beaudoin, G., Benali, H., and Rainville, P. (2009). Characterization of cardiac-related noise in BOLD-fMRI of the cervical spinal cord. Magnetic Resonance Imaging, 27, 300-310; E-pub:


Kunz, M., Chatelle, C., Lautenbacher, S., and Rainville, P. (2008). The relation between pain catastrophizing and facial responsiveness to pain. Pain, 140, 127-134;doi:10.1016/j.pain.2008.07.019.

Marc, I., Rainville, P., Masse, B., Verreault, R., Vaillancourt, L., Vallée, E. et Dodin, S. (2008). Hypnotic analgesia intervention during first-trimester pregnancy termination: an open randomized trial. Am J Obstet Gynecol, 199,469.e1-e9; doi:10.1016/j.ajog.2008.01.058 (Featured in Journal Club Section).

Duquette, M., Rainville, P., Alary, F., Lassonde, M., and Lepore, F (2008). Ipsilateral cortical representation of tactile and painful information in acallosal and callosotomized subjects. Neuropsychologia, 46, 2274-2279.

Khalfa, S., Roy, M., Rainville, P., Dalla Bella, S., Peretz, I. (2008). The role of tempo in the psychophysiological distinction between happy and sad music. International Journal of Psychophysiology, 68, 17-28.

Marc, I., Rainville, P., Dodin, S. (2008). Hypnotic induction and therapeutic suggestions in the chirurgical setting of the first trimester interruption of pregnancy. International Journal of Clinical and Experimental Hypnosis, 56, 214-228.

Simon, D., Craig, K.D. Gosselin, F., Belin, P., and Rainville, P. (2008). Recognition and discrimination of prototypical dynamic facial expression of pain and emotions. Pain, 135, 55-64.

Roy, M., Peretz, I., and Rainville, P. (2008). Emotional valence contributes to music-induced analgesia. Pain, 134, 140-7.


Albanese, M.C., Duerden, E.G., Rainville, P., Duncan, G.H. (2007). Memory traces of pain in human cortex. J. Neuroscience, 27, 4612-4620. (Featured in the page “This week in the Journal”).

Duquette, M. Roy, M., Leporé, F., Peretz, I., Rainville, P. (2007). Mécanismes cérébraux impliqués dans l’interaction entre la douleur et les émotions. Revue Neurologique, 163, 169-79.

Goffaux, P., Redmond, W.J., Rainville, P., and Marchand, S. (2007). Descending analgesia – When the spine echoes what the brain expects. Pain.130, 137-143. (A report on this article has been published in the ‘Research Highlights’ section of Nature Clinical Practice Neurology, 2007)

Marc, I., Rainville, P., Vaillancourt, L., Verreault, R., Masse, B. et Dodin, S. (2007). The use of hypnosis to improve pain management during voluntary interruption of pregnancy. An open randomized preliminary study. Contraception  75, 52-58.


Simon, D., Craig, K.D. et Miltner, W.H.R., Rainville, P.  (2006). Brain responses to dynamic facial expressions of pain. Pain, 126, 309-318. Front page of issue 1-3 of volume 126.

Jackson, P.L., Rainville, P., and Decety, J. (2006). To what extent do we share the pain of others? Insight from the neural bases of pain empathy. Pain 125, 5-9.

Rainville, P. et Duncan, G.H. (2006). Brain imaging studies of placebo analgesia: Methodological challenges and recommendations. Pain, 121, 177-180.

Rainville, P., Bechara, A., Naqvi, N., et Damasio, A.R. (2006). Basic emotions are associated with distinct patterns of cardiorespiratory activity. Int. J. Psychophysiol, 61, 5-18.

Charron, J., Rainville, P., et Marchand, S. (2006). Direct comparison of placeboeffects on clinical and experimental pain. Clinical Journal of Pain, 22, 204-211.


Rainville, P., Huyng Bao, Q.V., Chrétien, P. (2005). Pain-related emotions modulate experimental pain perception and autonomic responses. Pain, 118, 306-318.

Gallez, A., Rainville, P., Duncan, G.H. (2005). Habituation of sensory and affective responses to heat pain: evidence for contralateral mechanisms. J Neurophysiol., 94, 3509-3515.

Tousignant-Laflamme, Y., Rainville, P., Falanga, I., et Marchand, S. (2005). Establishing a link between heart rate and pain in healthy subjects: A gender effect. The Journal of Pain.6: 341-347.


Rainville, P., Doucet, J.C., Fortin, M.-C., et Duncan, G.H. (2004). Rapid deterioration of pain sensory-discriminative information in short-term memory. Pain, 110: 605-615.

Rainville, P. and Price, D.D. (2003). Hypnosis phenomenology and the neurobiology of consciousness.  The International Journal of Clinical and Experimental Hypnosis, 51, 105-129.

Price, D.D. Barrell, J.J., et Rainville, P. (2002). Integrating experiential-phenomenological methods and neuroscience to study neural mechanisms of pain and consciousness. Consciousness and Cognition, 11, 593-608.

Rainville, P., Hofbauer, R.K., Duncan, G.H., Bushnell, M.C., et Price, D.D. (2002). Hypnosis modulates activity in brain structures involved in the regulation of consciousness. Journal of Cognitive Neuroscience, vol. 14: 887-901.

Hofbauer, R.K., Rainville, P., Duncan, G.H., and Bushnell, M.C. (2001). Cortical representation of the sensory dimension of pain. Journal of Neurophysiology, 86, 402-411.

Logan H., Lutgendorf S., Rainville P., Sheffield D., Iverson K., Lubaroff D. (2001) Effects of stress and relaxation on capsaicin-induced pain. Journal of Pain, 2, 160-170.

Rainville, P., G.H. Duncan et Bushnell, M.C. (2000). Base cérébrale de l’expérience subjective de la douleur chez l’homme. Médecine science, 16, 519-527.


Rainville, P., Carrier, B., Hofbauer, R.K., Bushnell, M.C., et Duncan, G.H. (1999).  Dissociation of pain sensory and affective dimensions using hypnotic modulation. Pain, 82, 159-171.

Rainville, P., Chen, C.C., et Bushnell, M.C. (1999). Psychophysical study of noxious and innocuous cold discrimination in monkey. Experimental Brain Research, 125, 28-34.

Rainville, P., Hofbauer, R.K., Paus, T., Duncan, G.H., Bushnell, M.C., et Price, D.D.  (1999). Cerebral mechanisms of hypnotic induction and suggestion. Journal of Cognitive Neuroscience, 11, 110-125.

Rainville, P., Duncan, G.H., Price, D.D., Carrier, B., et Bushnell, M.C. (1997). Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science, 277, 968-970.

Chen, C.C., Rainville, P., et Bushnell, M.C. (1996). Noxious and innocuous cold discrimination in humans. Pain, 68, 33-43.

Rainville, P., Goulet, P., et Joanette, Y. (1995). Contribution of the right-hemisphere to the processing of concrete words. Clinical Aphasiology, 23, 207-216.

Rainville, P., Feine, J.S., Duncan, G.H., et Bushnell, M.C. (1992). A psychophysical comparison of sensory and affective responses to four modalities of experimental pain. Somatosensory and Motor Research, 9, 265-277.